University of California San Diego My Favourite Gene PRKN Parkin RBR E3 Discussion

I will provide you example and the questions that needed to be answered.

My favorite game is choose only one

choose one of these

1. Parkins

2. . Cystic fibrosis

3. COPD

Please just follow the direction and that is all.

Answer theses questions

My Favorite Gene

(5 pt)Why you were interested in examining this particular gene?

Part I. DNA & mRNA

(2 pt) From NCBI, find the Chromosome and structure (5’ ®3’)

(2 pt) Short list of homologs in other organisms (name and species)

(1 pt) Additional gene names (Preferred Names)

(1 pt) mRNA sequence (5’ ®3’)

(3 pt) Use the ExPasy online toolsto generate the 6 different potential open reading frames from a mRNA (cDNA) sequence

Part II. Protein & domain motifs

(2 pt) Actual Amino acid sequence

(1 pt) Using Graphic Summary Tab find function protein motifs

(2 pt) Using the BlastP program, do an alignment with the AA sequence with another species.

(5 pt)What useful, interesting, or insightful information you obtained from doing this exercise?

(1 pt)PubMed literature search (at least 5)