University of Florida How Natural Killer Cells Bind Antibody Coated Cells Discussion

1. Explain how NK (natural killer) cells can bind to antibody-coated cells and destroy these cells. (5 points)
2. Discuss how antibody-mediated opsonization and phagocytosis of microbes occurs. Include in your discussion the different types of human Fc receptors, and their cellular distribution as well as functions. (8 points)
3. What is the role of the complement system in host defense? Briefly describe how the complement system functions. (5 points)
4. Describe, in detail, how the alternative pathway is activated (4 points)
5. Describe, in detail, how the classical pathway is activated (4 points)
6. Describe, in detail, how the lectin pathway is activated (4 points)
7. Name and discuss one example of an inherited deficiency of regulatory proteins; find a journal article that discusses your chosen example and briefly discuss the article. (10 points)

Please include references